Description

Pemoline-D5 is a deuterated analog of the central nervous system stimulant pemoline, specifically labeled with five deuterium atoms. This stable isotope-labeled compound is a critical reference standard and internal standard for precise analytical quantification in research and development. It is primarily utilized by pharmaceutical researchers, forensic toxicologists, and analytical laboratories engaged in method development and validation. The compound enables accurate mass spectrometry-based analysis, ensuring reliable data for pharmacokinetic, metabolic, and doping control studies.

Application

• Internal Standard for LC-MS/MS: Serves as a crucial internal standard for the accurate quantification of pemoline and its metabolites in biological matrices using liquid chromatography-tandem mass spectrometry.
• Metabolic Studies: Used as a tracer in pharmaceutical research to investigate the metabolic pathways and pharmacokinetic profiles of pemoline.
• Forensic Toxicology: Employed in confirmatory testing and method validation for the detection of pemoline in doping control and forensic casework.
• Reference Material: Acts as a certified reference standard for calibrating analytical instruments and ensuring the accuracy and reproducibility of test methods.
• Drug Development Research: Supports analytical method development and validation in pre-clinical and clinical studies involving stimulant compounds.
• Quality Control: Used in pharmaceutical quality control laboratories to monitor and ensure the specificity of analytical procedures.

Basic Information

Product Name	Pemoline-D5
CAS No.	70838-73-2
Molecular Formula	C9H3D5N2O2
Molecular Weight	183.20 g/mol
Synonyms	2-Amino-5-phenyl-2-oxazolin-4-one-d5; 5-Phenyl-2-imino-4-oxazolidinone-d5; Pemoline (phenyl-d5); 2-Imino-5-phenyl-4-oxazolidinone-d5; 4,5-Dihydro-5-phenyl-2H-imidazol-4-one-d5; Phenyl-d5-pemoline; Stimol-d5; Cylert-d5 (deuterated)
EINECS	Contact for details

Quality Control

Our Pemoline-D5 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the deuterium content, chemical purity, and solvent residues. We adhere to relevant industry standards for reference materials to ensure data integrity and reliability for our clients' critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the product at 2-8°C. The compound is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥98 atom % D
Chemical Purity (NMR)	≥95%
Residual Solvent (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.