Description

Ribosomal Protein L7-L12 is a key component of the large ribosomal subunit, essential for protein synthesis and GTPase activity. This high-purity protein is critical for advanced biochemical research, structural biology studies, and the development of novel antimicrobial agents targeting the bacterial ribosome. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on molecular biology, antibiotic discovery, and proteomics.

Application

• Biochemical Research: Used as a fundamental reagent in studies of ribosome structure, function, and the mechanisms of protein biosynthesis.
• Antibiotic Development: Serves as a target protein for screening and evaluating new classes of antibacterial compounds that inhibit bacterial translation.
• Structural Biology: Essential for X-ray crystallography, cryo-electron microscopy (cryo-EM), and NMR studies to elucidate ribosomal architecture.
• Enzyme Activity Assays: Employed in in vitro assays to study GTPase activity and factor-dependent steps in translation.
• Diagnostic Kit Development: Can be used as a component or antigen in developing research-grade diagnostic tools for studying bacterial infections.
• Protein-Protein Interaction Studies: A vital tool for investigating interactions within the ribosome and with translational factors.

Basic Information

Product Name	Ribosomal Protein L7-L12
CAS No.	70815-33-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	50S Ribosomal Protein L7/L12; Ribosomal Protein L12; L7/L12 Ribosomal Protein; Protein L7/L12; 50S Subunit Protein L12; Acidic Ribosomal Protein P1/P2 (bacterial homolog); Bacterial Ribosomal Protein L7-L12; RP-L12
EINECS	Contact for details

Quality Control

Our Ribosomal Protein L7-L12 is produced and tested under stringent conditions to ensure the highest standards of purity and biological activity required for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional activity. We adhere to GMP-aligned guidelines for laboratory reagents to guarantee batch-to-batch consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Conforms
Purity (HPLC)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity (GTPase Assay)	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in appropriate buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.