Description

n-Cbz-Diethanolamine CAS NO 70782-12-6 is a protected diethanolamine derivative where the amine functionality is shielded by a carboxybenzyl (Cbz) group, a crucial feature for selective synthesis. This compound is a vital building block in organic and medicinal chemistry, enabling the controlled introduction of the diethanolamine moiety into more complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly those requiring a protected ethanolamine backbone.
• Peptide Synthesis: Serves as a protected linker or spacer molecule in solid-phase and solution-phase peptide chemistry.
• Ligand and Catalyst Development: Used to create chelating ligands for metal catalysts or as a precursor for functionalized materials.
• Polymer Modification: Acts as a monomer or functionalization agent for producing specialty polymers with hydroxyl and protected amine groups.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, or plant growth regulators.
• Bioconjugation Chemistry: Useful for creating cleavable linkers in antibody-drug conjugates (ADCs) or other bioconjugates.

Basic Information

Product Name	n-Cbz-Diethanolamine
CAS No.	70782-12-6
Molecular Formula	C12H17NO4
Molecular Weight	239.27 g/mol
Synonyms	N-Carboxybenzyl-diethanolamine; N-Cbz-2,2'-Iminodiethanol; 2,2'-[(Benzyloxycarbonyl)amino]diethanol; Diethanolamine, N-carbobenzoxy-; N-(Benzyloxycarbonyl)diethanolamine; Z-Diethanolamine; CBZ-Diethanolamine; N-Z-Diethanolamine
EINECS	Contact for details

Quality Control

Our n-Cbz-Diethanolamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.