Description

1-Aminocyclobutane-1-Carbonitrile is a versatile and high-value bicyclic nitrile building block. This compound is crucial for the synthesis of complex molecules, particularly in pharmaceutical research and development. It serves as a key intermediate for medicinal chemists and process R&D teams in the life sciences industry, enabling the construction of novel scaffolds with potential therapeutic activity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its strained cyclobutane ring to create molecules with unique biological activity.
• Material Science Research: Serves as a precursor for specialty polymers and advanced materials where the incorporation of a rigid, strained ring system is desired.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tool compounds for studying biological pathways and enzyme functions.
• Asymmetric Synthesis: Acts as a chiral synthon or precursor for chiral auxiliaries in stereoselective synthesis, important for producing enantiomerically pure compounds.
• Ligand Development: The aminonitrile moiety can be functionalized to create novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	1-Aminocyclobutane-1-Carbonitrile
CAS No.	70780-84-6
Molecular Formula	C5H8N2
Molecular Weight	96.13 g/mol
Synonyms	1-Aminocyclobutanecarbonitrile; 1-Cyano-1-aminocyclobutane; 1-Amino-1-cyanocyclobutane; Cyclobutane-1-carbonitrile, 1-amino-; 1-Aminocyclobutyl cyanide; Aminocyclobutanecarbonitrile; 1-Amino-cyclobutanecarbonitrile; 1-Amino-cyclobutane-1-carbonitrile
EINECS	Contact for details

Quality Control

Our 1-Aminocyclobutane-1-Carbonitrile is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.