Description

1-Chloro-2-Methyl-4-(Trifluoromethoxy)Benzene is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, combining chloro, methyl, and trifluoromethoxy substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring the trifluoromethoxy group for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the halogenated aromatic core contributes to biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of specialty chemicals for electronic displays and organic light-emitting diodes due to its aromatic and fluorinated nature.
• Polymer & Resin Modifier: Employed to introduce fluorine-containing side chains into polymers, altering their surface properties, chemical resistance, and durability.
• Organic Synthesis Reagent: A valuable substrate in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for constructing complex molecular architectures.

Basic Information

Product Name	1-Chloro-2-Methyl-4-(Trifluoromethoxy)Benzene
CAS No.	70692-42-1
Molecular Formula	C8H6ClF3O
Molecular Weight	210.58 g/mol
Synonyms	4-Chloro-3-methyl-1-(trifluoromethoxy)benzene; 2-Methyl-4-(trifluoromethoxy)chlorobenzene; 1-Chloro-2-methyl-4-(trifluoromethoxy)benzene; 3-Methyl-4-(trifluoromethoxy)chlorobenzene; 4-(Trifluoromethoxy)-2-methylchlorobenzene; Benzene, 1-chloro-2-methyl-4-(trifluoromethoxy)-; 70692-42-1
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-Methyl-4-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.