Description

n-Methyldimaprit is a potent and selective histamine H2 receptor agonist, widely recognized for its utility in pharmacological research and development. This compound is a critical tool for scientists investigating gastric acid secretion, cardiovascular function, and immune modulation pathways. It is primarily used by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in receptor studies and drug discovery programs.

Application

• Pharmacological Research: A standard reference agonist for studying histamine H2 receptor function, signaling, and desensitization.
• Drug Discovery: Used in high-throughput screening (HTS) assays to identify and characterize novel H2 receptor antagonists or modulators.
• Gastrointestinal Studies: Employed in vitro and in vivo models to investigate the regulation of gastric acid secretion and evaluate potential anti-ulcer therapeutics.
• Cardiovascular Research: Applied in studies examining the role of H2 receptors in heart rate and blood pressure regulation.
• Immunology & Inflammation: Utilized to probe the effects of H2 receptor activation on immune cell function (e.g., mast cells, T-cells) and inflammatory responses.
• Neuroscience: Serves as a tool compound to explore the central nervous system effects mediated by histamine receptors.

Basic Information

Product Name	n-Methyldimaprit
CAS No.	70674-98-5
Molecular Formula	C8H16N4S
Molecular Weight	200.30 g/mol
Synonyms	N-Methyldimaprit; SK&F 91488; 2-[[2-[(Dimethylamino)methyl]-1H-imidazol-4-yl]methylthio]-N-methyl-ethanamine; N-Methyl-S-[2-[(1-methyl-1H-imidazol-4-yl)methylthio]ethyl]isothiourea; 1-Methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]guanidine
EINECS	Contact for details

Quality Control

Our n-Methyldimaprit is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant quality standards for research chemicals to guarantee reliable and reproducible results for your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.