Description

H-Dl-Orn(Z)-Oh CAS NO 70671-51-1 is a protected derivative of the amino acid ornithine, featuring a benzyloxycarbonyl (Z) protecting group on the side chain amine. This compound is a crucial chiral building block and intermediate in advanced organic synthesis, particularly for the production of peptides and peptidomimetics. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development of bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for constructing peptides containing ornithine residues with orthogonal side-chain protection.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and for probing biological pathways involving polyamines.
• Prodrug Development: Acts as a linker or carrier moiety in the design of prodrugs to improve solubility, stability, or targeted delivery.
• Chemical Biology Tool: Utilized for labeling, cross-linking, or modifying biomolecules in proteomics and bioconjugation research.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	H-Dl-Orn(Z)-Oh
CAS No.	70671-51-1
Molecular Formula	C13H18N2O4
Molecular Weight	266.29 g/mol
Synonyms	N(alpha)-Z-DL-Ornithine; Z-DL-Orn-OH; Benzyloxycarbonyl-DL-ornithine; DL-2-Amino-5-[(benzyloxy)carbonylamino]pentanoic acid; N(5)-Carbobenzoxy-DL-ornithine; H-DL-Orn(Z)-OH; N(alpha)-Z-DL-Orn; (RS)-2-Amino-5-[(benzyloxycarbonyl)amino]pentanoic acid
EINECS	Contact for details

Quality Control

Our H-Dl-Orn(Z)-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.