Description

1-Cyclopentyl-3-(Trimethylsilyl)Prop-2-Yn-1-One is a specialized organosilicon building block featuring a cyclopentyl ketone and a trimethylsilyl-protected alkyne functional group. This unique structure makes it a valuable intermediate for advanced organic synthesis, particularly in the construction of complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for constructing complex carbon frameworks.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactive alkyne moiety for selective bond formation.
• Material Science Research: Serves as a precursor for advanced polymers or organic electronic materials where the silyl-protected alkyne allows for controlled polymerization or cross-linking.
• Organic Synthesis Building Block: Employed in Sonogashira coupling and other palladium-catalyzed cross-coupling reactions to introduce the cyclopentyl-acetylene unit into target molecules.
• Ligand and Catalyst Development: Utilized as a starting material for synthesizing specialized ligands or organometallic catalysts used in asymmetric synthesis.
• Academic and Industrial R&D: A critical reagent for methodological studies and exploring new synthetic pathways in chemistry laboratories worldwide.

Basic Information

Product Name	1-Cyclopentyl-3-(Trimethylsilyl)Prop-2-Yn-1-One
CAS No.	70639-94-0
Molecular Formula	C11H20OSi
Molecular Weight	196.36 g/mol
Synonyms	1-Cyclopentyl-3-(trimethylsilyl)prop-2-yn-1-one; 3-(Trimethylsilyl)-1-cyclopentyl-2-propyn-1-one; 1-Cyclopentyl-3-(trimethylsilyl)propiolone; Cyclopentyl 3-(trimethylsilyl)propiolyl ketone; TMS-Cyclopentylpropiolone; (Trimethylsilyl)cyclopentylpropynone; 70639-94-0; 1-Cyclopentyl-3-(trimethylsilyl)propiolic acid ketone
EINECS	Contact for details

Quality Control

Our 1-Cyclopentyl-3-(Trimethylsilyl)Prop-2-Yn-1-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.