Description

Cysteine Hydrazide is a specialized derivative of the amino acid cysteine, where the carboxylic acid group is replaced by a hydrazide moiety. This modification imparts unique reactivity, making it a valuable intermediate for the synthesis of heterocyclic compounds and as a building block in pharmaceutical research and peptide chemistry. It is particularly sought after by research institutions and manufacturers in the life sciences and fine chemical sectors for developing novel bioactive molecules and chemical probes.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing heterocyclic compounds with potential therapeutic activity, such as thiazolidines and other fused ring systems.
• Peptide Modification & Conjugation: Used to introduce hydrazide functional groups into peptides for site-specific labeling, bioconjugation, or the creation of peptide-drug conjugates.
• Chemical Biology Probes: Serves as a precursor for developing activity-based probes and affinity tags that target cysteine residues in proteins.
• Chelating Agent Synthesis: Utilized in the preparation of novel chelating ligands due to the presence of sulfur and nitrogen donor atoms.
• Organic Synthesis Reagent: Acts as a nucleophile in various organic transformations, including the synthesis of hydrazones and other functionalized molecules.
• Biochemical Research: Employed in studies investigating redox biology and thiol chemistry as a model or reagent compound.

Basic Information

Product Name	Cysteine Hydrazide
CAS No.	70470-68-7
Molecular Formula	C3H9N3O2S
Molecular Weight	151.19 g/mol
Synonyms	L-Cysteine Hydrazide; (2R)-2-Amino-3-sulfanylpropanehydrazide; Cys-NHNH2; Cysteine Hydrazide Hydrochloride (salt form); 3-Mercapto-L-alanine hydrazide; H-Cys-NHNH2; L-2-Amino-3-mercaptopropionic acid hydrazide
EINECS	Contact for details

Quality Control

Our Cysteine Hydrazide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specific range available on COA
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.