Description

N4-Ethyl-2'-Deoxycytidine CAS NO 70465-61-1 is a chemically modified nucleoside analog, specifically an ethylated derivative of deoxycytidine. This modification is crucial for imparting unique biochemical properties, making it a valuable intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, including antivirals and anticancer compounds, as well as in biochemical studies exploring nucleic acid chemistry and enzyme interactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in studies of DNA polymerases, nucleoside kinases, and other enzymes involved in nucleotide metabolism.
• Antisense Oligonucleotide Development: Serves as a modified base for incorporating into oligonucleotides to alter their stability, binding affinity, and biological activity.
• Proteomics & Genomics: Employed in the development of diagnostic tools and research kits for studying genetic expression and cellular processes.
• Chemical Biology Probes: Utilized to create labeled or tagged nucleosides for tracking and imaging applications within cellular systems.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	N4-Ethyl-2'-Deoxycytidine
CAS No.	70465-61-1
Molecular Formula	C11H17N3O4
Molecular Weight	255.27 g/mol
Synonyms	4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2(1H)-pyrimidinone, N-ethyl derivative; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-(ethylamino)-2(1H)-pyrimidinone; N4-Ethyl-2'-deoxycytidine; 2'-Deoxy-N4-ethylcytidine; N-Ethyl-2'-deoxycytidine; 4-N-Ethyl-2'-deoxycytidine; dC(Et)
EINECS	Contact for details

Quality Control

Our N4-Ethyl-2'-Deoxycytidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.