Description

4-S-(Hexane-6-Ol)Sulfidocyclophosphamide is a specialized organophosphorus compound, representing a chemically modified derivative of cyclophosphamide. This compound is significant for its potential as a key intermediate in advanced pharmaceutical research, particularly in the development of novel prodrugs and targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in oncology drug discovery, medicinal chemistry, and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anticancer prodrugs and targeted chemotherapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new analogs with improved efficacy and reduced toxicity profiles.
• Oncology Drug Discovery: A key precursor for developing next-generation alkylating agents designed for specific tumor targeting.
• Bioconjugation Studies: Utilized in research to create antibody-drug conjugates (ADCs) or other targeted delivery systems.
• Biochemical Research: Employed as a tool compound to study metabolic pathways and activation mechanisms of phosphoramide mustard derivatives.
• Academic & Institutional Research: Supports fundamental research in organic synthesis and bioorganic chemistry at universities and R&D centers.

Basic Information

Product Name	4-S-(Hexane-6-Ol)Sulfidocyclophosphamide
CAS No.	70396-85-9
Molecular Formula	C12H23N2O3PS
Molecular Weight	306.36 g/mol
Synonyms	4-(6-Hydroxyhexylthio)cyclophosphamide; 4-S-(6-Hydroxyhexyl)thiocyclophosphamide; Cyclophosphamide, 4-[(6-hydroxyhexyl)thio]-; NSC 757441; 4-Hydroxyhexylthio Cyclophosphamide; 4-(6-Hydroxyhexylsulfanyl)cyclophosphamide; 4-(6-Hydroxyhexylmercapto)cyclophosphamide
EINECS	Contact for details

Quality Control

Our 4-S-(Hexane-6-Ol)Sulfidocyclophosphamide is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.