Description

n-(o-Tolyl)-2,2,2-Trifluoroacetimidoyl Chlorid is a specialized organic intermediate featuring a reactive imidoyl chloride group and a trifluoromethyl moiety. This compound is valued for its role as a versatile building block in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research chemists and process development scientists working on the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing trifluoromethyl groups which enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with unique surface properties.
• Ligand and Catalyst Development: Employed in organic synthesis for constructing complex nitrogen-containing ligands used in catalytic systems.
• Fluorine Chemistry Research: An important reagent for introducing the CF3 group into target molecules, facilitating structure-activity relationship (SAR) studies.
• Custom Synthesis and Contract Manufacturing: A critical raw material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	n-(o-Tolyl)-2,2,2-Trifluoroacetimidoyl Chlorid
CAS No.	70314-81-7
Molecular Formula	C9H7ClF3NO
Molecular Weight	237.61 g/mol
Synonyms	N-(2-Methylphenyl)-2,2,2-trifluoroethanimidoyl Chloride; 2,2,2-Trifluoro-N-(o-tolyl)acetimidoyl Chloride; o-Tolyl Trifluoroacetimidoyl Chloride; 2-Methylphenyl Trifluoroacetimidoyl Chloride; 2,2,2-Trifluoroacet-o-toluidide Chloride; Trifluoroaceto-o-toluidide Chloride; N-(o-Tolyl)trifluoroacetimidoyl Chloride
EINECS	Contact for details

Quality Control

Our n-(o-Tolyl)-2,2,2-Trifluoroacetimidoyl Chlorid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and industrial synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, assay, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP environments for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases, strong oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.