Description

3-(3-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester is a high-value fluorinated aromatic ester, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the trifluoromethyl group, which imparts unique electronic and lipophilic properties to target molecules, enhancing their metabolic stability and bioavailability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring a trifluoromethylphenyl moiety for enhanced biological activity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of fluorinated components for electronic display and lighting technologies.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a substrate for exploring new fluorination methodologies in R&D laboratories.
• Flavor & Fragrance Industry: Potential intermediate for creating complex aromatic esters with modified stability and scent profiles.
• Polymer Modification: Used to introduce fluorine-containing side chains into polymers, altering their surface properties and chemical resistance.

Basic Information

Product Name	3-(3-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester
CAS No.	70311-33-0
Molecular Formula	C12H13F3O2
Molecular Weight	246.23 g/mol
Synonyms	Ethyl 3-[3-(Trifluoromethyl)phenyl]propanoate; 3-(3-Trifluoromethylphenyl)propionic Acid Ethyl Ester; Ethyl 3-(3-Trifluoromethylphenyl)propionate; m-Trifluoromethylhydrocinnamic Acid Ethyl Ester; 3-(m-Trifluoromethylphenyl)propionic Acid Ethyl Ester; Ethyl m-Trifluoromethylhydrocinnamate; 3-(3-(Trifluoromethyl)phenyl)propanoic Acid Ethyl Ester; 70311-33-0
EINECS	Contact for details

Quality Control

Our production of 3-(3-Trifluoromethyl-Phenyl)-Propionic Acid Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and GC for residual solvents, to ensure consistency and compliance with customer specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and meeting the rigorous standards required for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, organic solvents, fluorides, and strong alkalis. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Refractive Index	Contact for details
Density	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.