Description

Ethyl 3-(4-Fluorophenyl)-3-Hydroxypropanoate is a high-value fluorinated organic intermediate characterized by its chiral β-hydroxy ester functionality. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical sector, where it serves as a key building block for active pharmaceutical ingredients (APIs). It is essential for research and development chemists and production units in the pharmaceutical, agrochemical, and advanced material industries seeking reliable, high-purity intermediates for scalable synthesis.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of fluorinated drug candidates, including potential CNS agents and cardiovascular therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel fluorinated pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Chiral Building Block: Serves as a versatile precursor for asymmetric synthesis, enabling the construction of complex molecules with defined stereochemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where the 4-fluorophenyl moiety is required.
• Material Science Research: Investigated as a monomer or modifier in the development of advanced polymeric materials with specific optical or electronic properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	Ethyl 3-(4-Fluorophenyl)-3-Hydroxypropanoate
CAS No.	70200-12-3
Molecular Formula	C11H13FO3
Molecular Weight	212.22 g/mol
Synonyms	Ethyl 3-Hydroxy-3-(4-fluorophenyl)propanoate; 3-(4-Fluorophenyl)-3-hydroxypropionic Acid Ethyl Ester; β-Hydroxy-β-(4-fluorophenyl)propionic Acid Ethyl Ester; 4-Fluoro-β-hydroxyhydrocinnamic Acid Ethyl Ester; Ethyl 4-Fluoro-β-hydroxyhydrocinnamate; (RS)-Ethyl 3-(4-Fluorophenyl)-3-hydroxypropanoate; (±)-Ethyl 3-(4-Fluorophenyl)-3-hydroxypropionate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(4-Fluorophenyl)-3-Hydroxypropanoate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.