Description

11-Nortetrodotoxin is a potent neurotoxin and a key structural analog of tetrodotoxin, a sodium channel blocker of significant scientific interest. This compound is essential for advanced pharmacological research, serving as a critical tool for studying ion channel function and neurophysiology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neuroscience, toxicology, and drug discovery programs.

Application

• Neuroscience Research: As a selective sodium channel blocker for electrophysiological studies of neuronal signaling and action potential generation.
• Pharmacological Tool Compound: Used in receptor binding assays and functional studies to investigate the structure-activity relationships of neurotoxins.
• Toxicology Studies: Employed as a reference standard in the analysis and detection of tetrodotoxin and related marine toxins.
• Drug Discovery: Serves as a molecular scaffold or probe in the development of novel analgesics or local anesthetics targeting voltage-gated sodium channels.
• Academic Research: Fundamental studies in biochemistry and physiology to understand toxin mechanisms and ion channel biophysics.

Basic Information

Product Name	11-Nortetrodotoxin
CAS No.	70170-72-8
Molecular Formula	C₁₁H₁₇N₃O₈
Molecular Weight	319.27 g/mol
Synonyms	11-Deoxytetrodotoxin; 11-Nor-TTX; 4,9-Anhydro-11-nortetrodotoxin; Tetrodotoxin, 11-nor-; Tetrodotoxin analog; TTX analog; Sodium channel blocker analog
EINECS	Contact for details

Quality Control

Our 11-Nortetrodotoxin is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.