Description

Baclofen-D4 CAS NO 70155-52-1 is a stable isotope-labeled analog of the pharmaceutical agent Baclofen, where four hydrogen atoms are replaced by deuterium. This high-purity compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the accuracy and reliability of analytical data. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and analytical testing facilities engaged in drug metabolism, pharmacokinetic (PK/PD) studies, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS analysis in bioanalytical studies.
• Quantitative reference material for pharmacokinetic (PK) and pharmacodynamic (PD) research.
• Use in drug metabolism and disposition studies to track parent drug and metabolites.
• Critical component in the development and validation of GLP/GCP-compliant analytical methods.
• Calibration standard for ensuring accuracy in therapeutic drug monitoring (TDM) assays.
• Research tool in neuroscience and pharmacology for investigating GABAB receptor activity.

Basic Information

Product Name	Baclofen-D4
CAS No.	70155-52-1
Molecular Formula	C10H8D4ClNO2
Molecular Weight	217.68 g/mol (for C10H8D4ClNO2)
Synonyms	4-Amino-3-(4-chlorophenyl)-D4-butyric acid; β-(4-Chlorophenyl)-γ-aminobutyric acid-D4; Baclofen (phenyl-D4); Lioresal-D4; Gablofen-D4; (RS)-Baclofen-D4; 3-(4-Chlorophenyl)-4-aminobutyric acid-D4
EINECS	Contact for details

Quality Control

Our Baclofen-D4 is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity by HPLC, and confirmation of structure. We adhere to relevant industry standards for reference materials to guarantee reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-enrichment)	≥98.0 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.