Description

5-Fluorobenzo[B]Thiophene is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorine or the benzo[b]thiophene scaffold into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the fluorinated thiophene moiety can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for organic semiconductors, liquid crystals, and conductive polymers due to the electron-rich nature of the thiophene ring.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development, such as cross-coupling reactions, fluorination studies, and heterocycle functionalization.
• Fluorine Chemistry Studies: Acts as a model substrate for investigating the effects of fluorine substitution on the reactivity and physical properties of fused-ring heterocyclic systems.

Basic Information

Product Name	5-Fluorobenzo[B]Thiophene
CAS No.	70060-12-7
Molecular Formula	C8H5FS
Molecular Weight	152.19 g/mol
Synonyms	5-Fluorobenzo[b]thiophene; 5-Fluorobenzo[b]thiophene; 5-Fluoro-1-benzothiophene; 5-Fluoro-benzo[b]thiophene; 5-Fluorobenzothiophene; Benzo[b]thiophene, 5-fluoro-; 70060-12-7
EINECS	Contact for details

Quality Control

Our 5-Fluorobenzo[B]Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.