Description

2-Methyl-5-Nitro-1H-Imidazole-1-Propanol Monohydrochloride is a high-purity, pharmaceutically relevant intermediate characterized by its nitroimidazole core structure. This compound is critical for ensuring the quality and efficacy of downstream active pharmaceutical ingredients (APIs) in regulated manufacturing processes. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiprotozoal and antibacterial agents.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates targeting anaerobic bacteria and parasites.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Chemical Synthesis: Employed in organic synthesis to introduce the 2-methyl-5-nitroimidazole moiety into more complex molecular architectures.

Basic Information

Product Name	2-Methyl-5-Nitro-1H-Imidazole-1-Propanol Monohydrochloride
CAS No.	70028-95-4
Molecular Formula	C7H12ClN3O3
Molecular Weight	221.64 g/mol
Synonyms	1-(3-Hydroxypropyl)-2-methyl-5-nitroimidazole hydrochloride; 2-Methyl-5-nitro-1-(3-hydroxypropyl)imidazole hydrochloride; 5-Nitro-1-(3-hydroxypropyl)-2-methylimidazole hydrochloride; Metronidazole Impurity C (Hydrochloride Salt); 1H-Imidazole-1-propanol, 2-methyl-5-nitro-, monohydrochloride; MNIP HCl
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-Nitro-1H-Imidazole-1-Propanol Monohydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.