Description

Des-Asn(20)-Beta(C)-Endorphin CAS NO 70023-09-5 is a specific, truncated analog of the endogenous neuropeptide β-Endorphin. This compound is of significant value in biochemical and pharmacological research for studying opioid receptor interactions, peptide structure-activity relationships, and neuroendocrine signaling pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on neuroscience, pain management, and endocrinology.

Application

• Neuroscience Research: Used as a reference standard and tool compound for investigating the endogenous opioid system, receptor binding assays, and signal transduction studies.
• Pharmacological Studies: Critical for structure-activity relationship (SAR) analysis to develop novel analgesics or modulators of opioid receptor function with potentially reduced side effects.
• Biochemical Assay Development: Serves as a key antigen or standard in the development of immunoassays (ELISA, RIA) for detecting and quantifying endorphin-related peptides.
• Academic & Clinical Research: Employed in studies exploring the role of endorphins in stress response, pain perception, addiction, and mood disorders.
• Pharmaceutical R&D: Utilized in high-throughput screening (HTS) campaigns and preclinical testing to identify and validate new therapeutic targets within the opioid pathway.

Basic Information

Product Name	Des-Asn(20)-Beta(C)-Endorphin
CAS No.	70023-09-5
Molecular Formula	C145H230N40O42S
Molecular Weight	3280.7 g/mol
Synonyms	β-C-Endorphin (human), Des-Asparagine-20-β-C-Endorphin; β-Endorphin (1-19); β-Endorphin (1-19), human; β-C-Endorphin, Des-Asn(20)-; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-OH; [Des-Asn20]-β-endorphin (human); β-Lipotropin (61-79), human
EINECS	Contact for details

Quality Control

Our Des-Asn(20)-Beta(C)-Endorphin is manufactured under strict quality systems suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity determination and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, analytical methods, and batch-specific data are available upon request to ensure full traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.