Description

2-Acetamido-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranose is a key protected intermediate in carbohydrate and nucleoside chemistry. This compound matters for its role as a versatile building block in the synthesis of complex bioactive molecules, offering a stable, acetylated precursor that facilitates selective deprotection and further functionalization. It is primarily needed by pharmaceutical R&D teams, academic research laboratories, and fine chemical manufacturers focused on developing glycosidase inhibitors, antiviral agents, and novel glycoconjugates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of N-acetylglucosamine derivatives, neuraminidase inhibitors, and other glycosidase-targeting therapeutic agents.
• Antiviral Drug Synthesis: Used in the research and development of nucleoside analogs and sialic acid mimetics with potential antiviral activity.
• Glycobiology Research: Serves as a protected glycosyl donor or acceptor for constructing complex oligosaccharides and glycopeptides in biochemical studies.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, chiral auxiliaries, and labeled compounds for analytical standards.
• Cosmetic Ingredient Synthesis: A starting material for producing hyaluronic acid precursors and other skin-conditioning agents.
• Bioconjugation Chemistry: Facilitates the site-specific modification of proteins and peptides with carbohydrate moieties for drug delivery and diagnostic applications.

Basic Information

Product Name	2-Acetamido-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranose
CAS No.	7784-54-5
Molecular Formula	C16H23NO10
Molecular Weight	389.36 g/mol
Synonyms	1,3,4,6-Tetra-O-acetyl-2-acetamido-2-deoxy-α-D-glucopyranose; N-Acetylglucosamine Tetraacetate (α-form); GlcNAc Tetraacetate; 2-Acetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α-D-glucopyranose; α-D-GlcNAc(Ac)4; N-Acetyl-α-D-glucosamine Tetraacetate; Peracetylated N-Acetylglucosamine (α-anomer); 2-(Acetylamino)-2-deoxy-1,3,4,6-tetra-O-acetyl-α-D-glucopyranose
EINECS	232-079-3

Quality Control

Our 2-Acetamido-2-Deoxy-1,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with research and pharmaceutical-grade standards. Certificates of Analysis (COA) detailing specific results for purity, chiral purity, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity ([α]D)	Specific rotation provided per batch
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Melting Point	Characteristic range provided

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.