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iso-Propyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside CAS NO 7772-85-2
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CAS No.:7772-85-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
iso-Propyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is a key protected glycosyl donor and advanced intermediate in carbohydrate chemistry. This compound is critical for the controlled synthesis of complex oligosaccharides and glycoconjugates, enabling research and production in life sciences. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic laboratories focused on glycoscience, drug discovery, and the development of novel therapeutics and diagnostics.
Application
- Glycosylation Reactions: Serves as a crucial glycosyl donor in the stereoselective synthesis of O-linked and N-linked glycans.
- Pharmaceutical Intermediates: An advanced building block for the development of carbohydrate-based drugs, including antiviral and anticancer agents.
- Oligosaccharide Synthesis: Used in the automated and manual assembly of complex oligosaccharide chains for research and diagnostic applications.
- Glycoconjugate Production: A precursor in the creation of glycoproteins, glycolipids, and neoglycoconjugates for vaccine development and biomarker studies.
- Chemical Biology Probes: Enables the synthesis of tagged carbohydrate probes for studying glycan-protein interactions and cellular processes.
- Enzyme Substrate Studies: Used as a substrate or inhibitor in enzymatic assays for glycosyltransferases and glycosidases.
Basic Information
| Product Name | iso-Propyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside |
| CAS No. | 7772-85-2 |
| Molecular Formula | C₁₇H₂₇NO₉ |
| Molecular Weight | 389.40 g/mol |
| Synonyms | 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl isopropyl ether; Isopropyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside; Isopropyl N-acetyl-β-D-glucosaminide triacetate; 1-O-Isopropyl-2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranose; β-D-GlcNAc(OAc)₃-O-iPr; N-Acetyl-β-D-glucosamine triacetate isopropyl glycoside |
| EINECS | Contact for details |
Quality Control
Our iso-Propyl 2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-β-D-Glucopyranoside is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to research or cGMP-grade requirements upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Specific Rotation [α]²⁰D | -15° to -25° (c=1 in CHCl₃) |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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