Description

2'-Nor Thiamine is a key thiamine (Vitamin B1) derivative and a vital intermediate in the synthesis of advanced pharmaceutical compounds. Its precise molecular structure makes it an essential building block for creating specialized thiamine analogs and active pharmaceutical ingredients (APIs). This high-purity intermediate is primarily required by research institutions and manufacturers in the pharmaceutical and nutraceutical sectors for developing new therapeutic and nutritional formulations.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel thiamine-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and building block in metabolic pathway studies and enzymatic research.
• Nutraceutical Development: Serves as an intermediate for creating specialized vitamin B1 derivatives in advanced nutritional supplements.
• Analytical Standard: Employed as a high-purity standard in HPLC and LC-MS methods for quality control and assay development.
• Organic Synthesis: Valuable synthon for medicinal chemists in constructing complex molecules for biological screening.

Basic Information

Product Name	2'-Nor Thiamine
CAS No.	7770-93-6
Molecular Formula	C11H16N4OS
Molecular Weight	252.34 g/mol
Synonyms	2'-Deoxythiamine; 2'-Norvitamin B1; 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium Chloride; Thiamine Impurity; Vitamin B1 Derivative; Thiamine Related Compound; 2'-Nor-thiamine Chloride
EINECS	Contact for details

Quality Control

Our 2'-Nor Thiamine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.