Description

Boc-D-Alanine is a high-purity, enantiomerically pure amino acid derivative widely used as a critical building block in organic synthesis. Its primary value lies in providing a protected D-alanine moiety, essential for the controlled construction of peptides and peptidomimetics. This product is indispensable for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex biomolecules.

Application

• Peptide Synthesis: A fundamental building block in solid-phase and solution-phase peptide synthesis (SPPS) for incorporating D-alanine residues.
• Pharmaceutical Intermediates: Key intermediate in the research and production of chiral drugs, antibiotics, and enzyme inhibitors.
• Bioconjugation & Labeling: Used in the preparation of modified peptides for biochemical studies, diagnostics, and targeted drug delivery systems.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group allows for orthogonal protection strategies in multi-step synthetic sequences.
• Combinatorial Chemistry: Employed in the generation of diverse chemical libraries for high-throughput screening in drug discovery.
• Academic & Industrial R&D: Serves as a standard reagent in research laboratories for studying peptide structure, function, and stability.

Basic Information

Product Name	Boc-D-Alanine
CAS No.	7764-95-6
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)propanoic acid; D-2-[(tert-Butoxycarbonyl)amino]propionic acid; N-(tert-Butoxycarbonyl)-D-alanine; N-Boc-D-alanine; Boc-D-Ala-OH; BOC-D-ALA; Boc-D-Ala; (R)-2-(Boc-amino)propionic acid
EINECS	231-850-8

Quality Control

Our Boc-D-Alanine CAS NO 7764-95-6 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity (typically ≥98.5% by HPLC), enantiomeric excess, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Specific Rotation	-24.0° to -28.0° (c=1 in Acetic Acid)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.