Description

2-(4-Fluorobenzoyl)Acetic Acid is a versatile fluorinated aromatic keto acid derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its ability to introduce both a fluorinated aromatic ring and a reactive acetic acid moiety into target molecules, enabling the development of compounds with enhanced biological activity and specific physicochemical properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic molecules where the fluorine atom can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorobenzoyl group can contribute to increased efficacy and environmental selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials that require fluorinated aromatic components.
• Chemical Research & Development: A valuable reagent for constructing complex heterocyclic compounds, such as furans, pyrroles, and pyrazoles, through various condensation and cyclization reactions.

Basic Information

Product Name	2-(4-Fluorobenzoyl)Acetic Acid
CAS No.	7761-30-0
Molecular Formula	C9H7FO3
Molecular Weight	182.15 g/mol
Synonyms	4'-Fluorobenzoylacetic Acid; (4-Fluorobenzoyl)acetic Acid; 2-(4-Fluorobenzoyl)ethanoic Acid; 4-Fluorophenacylcarboxylic Acid; p-Fluorobenzoylacetic Acid; 4-Fluorobenzoylacetic Acid; 2-Oxo-2-(4-fluorophenyl)acetic Acid; α-Oxo-4-fluorobenzeneacetic Acid
EINECS	231-828-3

Quality Control

Our 2-(4-Fluorobenzoyl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.