Description

H-Gly-His-Gly-Oh CAS NO 7758-33-0 is a high-purity tripeptide derivative consisting of glycine, histidine, and glycine with a free carboxylic acid terminus. This compound serves as a critical building block and biochemical tool in advanced research and development. It is primarily utilized by professionals in the pharmaceutical, biotechnology, and life science sectors for applications ranging from peptide synthesis to enzymatic studies.

Application

• Pharmaceutical Intermediate: Used as a key precursor in the synthesis of more complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic assays to study protease and peptidase activity.
• Cell Culture & Media Supplement: Acts as a component in specialized cell culture media to support specific metabolic pathways.
• Cosmetic Peptide Synthesis: Incorporated into the development of bioactive peptides for skincare and cosmetic formulations.
• Nutritional Science: Studied for its potential role in metal ion chelation and bioavailability in nutritional supplements.
• Diagnostic Reagent Development: Utilized in the creation of calibration standards and reagents for clinical diagnostics.

Basic Information

Item	Detail
Product Name	H-Gly-His-Gly-Oh
CAS No.	7758-33-0
Molecular Formula	C11H16N6O4
Molecular Weight	296.28 g/mol
Synonyms	Glycyl-L-histidylglycine; G-H-G-OH; H-Gly-His-Gly; Gly-His-Gly; L-Histidylglycylglycine; G-H-G; Tripeptide G-H-G; 2-[[2-[(2-Aminoacetyl)amino]-3-(1H-imidazol-4-yl)propanoyl]amino]acetic acid
EINECS	Contact for details

Quality Control

Our H-Gly-His-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.