Description

Boc-Lys-Otbu CAS NO 7750-42-7 is a protected derivative of the essential amino acid L-lysine, featuring tert-butyloxycarbonyl (Boc) and tert-butyl ester (OtBu) protecting groups on its amine and carboxyl functionalities, respectively. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled, sequential assembly of complex peptides and proteins. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in the production of therapeutic peptides, biochemical probes, and novel biomaterials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental Nα-Boc protected amino acid derivative for the Merrifield method, allowing for the precise construction of peptide chains.
• Pharmaceutical Intermediates: Serves as a key intermediate in the research and development of peptide-based drugs, including hormones, antibiotics, and targeted therapies.
• Bioconjugation and Labeling: Used to introduce lysine residues with orthogonal protecting groups for subsequent site-specific modification with fluorescent dyes, affinity tags, or other functional moieties.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening in drug discovery programs.
• Biochemical Research: Essential for academic and industrial research involving protein engineering, structure-activity relationship (SAR) studies, and epitope mapping.
• Custom Peptide Service Providers: A staple raw material for CROs and CDMOs offering bespoke peptide synthesis services to the global life science community.

Basic Information

Product Name	Boc-Lys-Otbu
CAS No.	7750-42-7
Molecular Formula	C16H32N2O4
Molecular Weight	316.44 g/mol
Synonyms	Nα-Boc-Nε-Z-L-lysine tert-butyl ester; Nα-Boc-Nε-Cbz-L-lysine tert-butyl ester; Boc-Lys(Z)-OtBu; tert-Butyl N-[(2S)-6-{[(benzyloxy)carbonyl]amino}-2-{[(tert-butoxy)carbonyl]amino}hexanoate]; (S)-2-((tert-Butoxycarbonyl)amino)-6-((benzyloxycarbonyl)amino)hexanoic acid tert-butyl ester; Boc-Lys(Cbz)-OtBu; Nα-Boc-Nε-benzyloxycarbonyl-L-lysine tert-butyl ester
EINECS	Contact for details

Quality Control

Our Boc-Lys-Otbu is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistent enantiomeric integrity, meeting the exacting standards required for peptide synthesis. Certificates of Analysis (COA) detailing purity (by HPLC), chiral purity, appearance, and other relevant specifications are provided with every shipment to ensure full traceability and compliance with your research or production protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.