Description

Salicylic Acid B-D-o-Glucuronide is a key conjugated metabolite of salicylic acid, formed via glucuronidation in biological systems. This compound is essential for researchers and manufacturers requiring a high-purity reference standard for analytical and metabolic studies. It is primarily utilized in the pharmaceutical, biotechnology, and diagnostic sectors for applications such as drug metabolism and pharmacokinetics (DMPK) research, biomarker analysis, and the development of analytical methods.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the quantification and identification of salicylic acid metabolites in bioanalytical assays.
• Drug Metabolism & Pharmacokinetics (DMPK): Critical for in vitro and in vivo studies to understand the metabolic pathways, clearance, and bioavailability of salicylate-based drugs.
• Biomarker Research: Used in clinical and preclinical studies to investigate exposure levels and metabolic profiles of salicylates.
• Analytical Method Development: Employed as a calibrant in HPLC, LC-MS, and other chromatographic techniques to validate methods for metabolite detection.
• Enzymology Studies: Acts as a substrate or product for studying the activity of UDP-glucuronosyltransferase (UGT) enzymes.
• Diagnostic Kit Manufacturing: A potential component in the formulation of diagnostic assays and kits for therapeutic drug monitoring.

Basic Information

Product Name	Salicylic Acid B-D-o-Glucuronide
CAS No.	7695-70-7
Molecular Formula	C₁₃H₁₄O₉
Molecular Weight	314.24 g/mol
Synonyms	Salicyluric Acid Glucuronide; 2-[(2-Carboxyphenoxy)carbonyl]phenyl-β-D-glucopyranosiduronic Acid; β-D-Glucopyranosiduronic Acid, 2-[(2-carboxyphenoxy)carbonyl]phenyl; Salicylic Acid β-D-Glucuronide; O-Salicyloyl-β-D-glucuronic Acid; Salicyloyl Glucuronide; 2-Hydroxybenzoyl-β-D-glucuronide
EINECS	Contact for details

Quality Control

Our Salicylic Acid B-D-o-Glucuronide is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant pharmacopeial and research standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.