Description

1,4-Bis(Diphenylphosphino)Butane is a high-purity bidentate phosphine ligand widely used in organometallic chemistry and catalysis. Its primary value lies in its ability to coordinate with transition metals to form highly active and selective catalysts for a variety of synthetic transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in cross-coupling, hydrogenation, and hydroformylation reactions.

Application

• Homogeneous Catalysis: A key ligand for palladium, rhodium, and platinum catalysts in cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira).
• Asymmetric Synthesis: Used in the preparation of chiral catalysts for enantioselective hydrogenation and other transformations.
• Polymerization Catalysis: Serves as a ligand in metal-catalyzed polymerization processes for specialty polymers.
• Pharmaceutical Intermediates: Facilitates the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides.
• Material Science Research: Used in the development of novel organometallic complexes and functional materials.
• Hydrogenation Reactions: Acts as a ligand for catalysts in the selective reduction of alkenes, alkynes, and other functional groups.
• Laboratory Reagent: A valuable building block and reagent for academic and industrial R&D in synthetic chemistry.

Basic Information

Product Name	1,4-Bis(Diphenylphosphino)Butane
CAS No.	7688-25-7
Molecular Formula	C28H28P2
Molecular Weight	426.47 g/mol
Synonyms	1,4-Bis(diphenylphosphino)butane; DPPB; Butanediylbis(diphenylphosphine); 1,4-Bis(diphenylphosphanyl)butane; NSC 168088; Bis(diphenylphosphino)butane; Diphos (related, but specific to 1,2-bis(diphenylphosphino)ethane); Ph2P(CH2)4PPh2
EINECS	231-672-8

Quality Control

Our 1,4-Bis(Diphenylphosphino)Butane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing specific batch results are provided and can be tailored to meet the requirements of cGMP, ISO, or other relevant quality standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at room temperature (15-25°C). This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	138 - 142 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.