Description

n-o-Nps-L-Asparagine is a protected derivative of the amino acid L-asparagine, featuring an o-nitrophenylsulfenyl (Nps) protecting group on the amine functionality. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of complex peptides and proteins. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-purity, specialized amino acid derivatives for advanced research and production.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled, sequential addition of asparagine residues.
• Pharmaceutical Research: For the development and production of peptide-based therapeutics, hormones, and vaccines.
• Bioconjugation: Used in the site-specific modification of peptides and proteins for drug delivery systems.
• Biochemical Research: As a reagent for studying enzyme mechanisms, protein folding, and structure-activity relationships.
• Combinatorial Chemistry: Employed in the generation of diverse peptide libraries for drug discovery screening.
• Protecting Group Chemistry: Serves as a model compound for studying the properties and cleavage conditions of the Nps protecting group.

Basic Information

Item	Detail
Product Name	n-o-Nps-L-Asparagine
CAS No.	7685-72-5
Molecular Formula	C₁₀H₁₁N₃O₆S
Molecular Weight	301.27 g/mol
Synonyms	N-(2-Nitrophenylsulfenyl)-L-asparagine; L-Asparagine, N-[(2-nitrophenyl)thio]-; o-Nps-L-Asn; Nps-L-Asn-OH; 2-Nitrophenylsulfenyl-L-asparagine; N-2-Nitrophenylsulfenylasparagine; N-(o-Nitrophenylthio)-L-asparagine; NPS-L-Asparagine
EINECS	Contact for details

Quality Control

Our n-o-Nps-L-Asparagine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.