Description

4,5-Diamino-2-Fluoro-5-Oxovaleric Acid Hydrochloride is a high-purity, specialized organic building block of significant interest in advanced synthetic chemistry. Its unique structure, featuring both amino and carboxylic acid functionalities alongside a fluorine atom, makes it a valuable precursor for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. Its reliable quality and consistent supply are critical for ensuring the reproducibility of complex multi-step synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting specific enzyme inhibition or receptor binding.
• Peptide Synthesis: Used in the preparation of fluorinated amino acid analogs for incorporation into peptides, modifying their stability, bioavailability, and biological activity.
• Chemical Biology Research: Serves as a probe or precursor in the study of metabolic pathways and protein interactions due to its fluorine label and reactive handles.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides or pesticides where the fluorine moiety can enhance efficacy and environmental stability.
• Material Science: Potential use as a monomer or cross-linking agent in the development of specialized polymers with unique surface properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses producing bespoke compounds for client R&D programs.

Basic Information

Product Name	4,5-Diamino-2-Fluoro-5-Oxovaleric Acid Hydrochloride
CAS No.	7682-58-8
Molecular Formula	C5H10FN2O3 • HCl
Molecular Weight	212.61 g/mol (Free base: 176.15 g/mol)
Synonyms	2-Fluoro-4,5-diamino-5-oxopentanoic acid hydrochloride; 4,5-Diamino-2-fluoroglutaric acid 5-amide hydrochloride; 2-Fluoroglutamine acid derivative hydrochloride; 5-Amino-4-[(aminocarbonyl)amino]-2-fluoropentanoic acid hydrochloride; (2R/S)-4,5-Diamino-2-fluoro-5-oxopentanoic acid hydrochloride; L-Glutamine, 2-fluoro-, hydrochloride (derivative); Fluoroglutamine derivative HCl
EINECS	Contact for details

Quality Control

Our 4,5-Diamino-2-Fluoro-5-Oxovaleric Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and heavy metals. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production standards. Specifications can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.