Description

Ac-Dl-Nva-Oh is a protected amino acid derivative, specifically the acetylated form of DL-norvaline. This compound serves as a crucial building block and intermediate in advanced organic synthesis, particularly in the preparation of peptides and other bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require high-purity chiral precursors for drug discovery and development.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid residue in solid-phase and solution-phase peptide chemistry to construct complex peptide sequences.
• Biochemical Research: Serves as a standard or reagent in metabolic studies and enzyme inhibition assays due to its modified amino acid structure.
• Fine Chemical Production: Acts as a chiral synthon for the manufacture of specialty chemicals, flavors, and fragrances.
• Protecting Group Strategy: The acetyl (Ac) group protects the amine functionality, allowing for selective reactions at other sites during multi-step syntheses.

Basic Information

Product Name	Ac-Dl-Nva-Oh
CAS No.	7682-15-7
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	N-Acetyl-DL-norvaline; Ac-DL-Nva-OH; DL-2-Acetamidopentanoic acid; 2-Acetamidopentanoic acid; N-Acetylnorvaline; Ac-Nva-OH; Norvaline, N-acetyl-, DL-; NSC 3349
EINECS	Contact for details

Quality Control

Our Ac-Dl-Nva-Oh is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available upon request. We adhere to cGMP standards for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	DL-mixture
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.