Description

n-o-Nitrophenylsulfenyl-L-Hydroxyproline Di(Cyclohexyl)Ammonium Salt is a specialized, protected amino acid derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating complex peptide coupling reactions, particularly where the stereochemistry of hydroxyproline must be preserved. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Peptide Synthesis: Acts as a key protected intermediate for the solid-phase and solution-phase synthesis of complex peptides containing hydroxyproline residues.
• Pharmaceutical Research: Used in the research and development of peptide drugs, hormone analogs, and enzyme inhibitors where precise amino acid incorporation is required.
• Bioconjugation: Serves as a reagent for the site-specific modification of peptides and proteins in bioconjugation chemistry.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides and activity-based probes for studying biological processes and drug-target interactions.
• Academic & Industrial R&D: A valuable tool for synthetic chemists in academia and industry exploring new synthetic methodologies and peptide mimetics.

Basic Information

Product Name	n-o-Nitrophenylsulfenyl-L-Hydroxyproline Di(Cyclohexyl)Ammonium Salt
CAS No.	7675-54-9
Molecular Formula	C23H35N3O5S
Molecular Weight	465.61 g/mol
Synonyms	NSC 334087; L-Hydroxyproline, N-[(4-nitrophenyl)thio]-, compd. with N,N-dicyclohexylamine (1:1); o-Nitrophenylsulfenyl-L-hydroxyproline Dicyclohexylammonium Salt; (2S,4R)-1-[(4-Nitrophenyl)sulfanyl]-4-hydroxypyrrolidine-2-carboxylic acid - N,N-Dicyclohexylamine (1:1); Nps-Hyp-OH·DCHA; Nps-L-Hydroxyproline Dicyclohexylammonium Salt
EINECS	Contact for details

Quality Control

Our n-o-Nitrophenylsulfenyl-L-Hydroxyproline Di(Cyclohexyl)Ammonium Salt is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and specific test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% (L-isomer)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.