Description

n-2-Nitrophenylsulfenyl-L-Leucine Dicyclohexylammonium Salt is a specialized, high-purity chemical intermediate primarily used in advanced peptide synthesis and pharmaceutical research. This compound serves as a critical building block for the controlled introduction of the leucine amino acid residue under specific, protected conditions. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for complex organic synthesis. The product is supplied with rigorous quality control to ensure batch-to-batch consistency for sensitive applications.

Application

• Peptide Synthesis: Acts as a key protected amino acid derivative for solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediate: Used in the research and development of novel therapeutic peptides and peptidomimetics.
• Biochemical Research: Employed in studies involving protein structure, function, and enzyme-substrate interactions.
• Protecting Group Chemistry: Utilizes the 2-nitrophenylsulfenyl (Nps) group for selective protection of amino functionalities in multi-step syntheses.
• Fine Chemical Production: Serves as a precursor in the manufacture of complex, high-value organic molecules.
• Academic Research: A valuable reagent for university and institutional laboratories focused on organic and medicinal chemistry.

Basic Information

Item	Details
Product Name	n-2-Nitrophenylsulfenyl-L-Leucine Dicyclohexylammonium Salt
CAS No.	7675-50-5
Molecular Formula	C24H39N3O4S
Molecular Weight	465.65 g/mol
Synonyms	L-Leucine, N-[(2-nitrophenyl)thio]-, compd. with N-cyclohexylcyclohexanamine (1:1); N-2-Nitrophenylsulfenyl-L-leucine dicyclohexylammonium salt; Nps-Leu-OH·DCHA; 2-Nitrophenylsulfenyl-L-leucine dicyclohexylamine salt; Nps-L-Leucine DCHA salt; (S)-2-((2-Nitrophenyl)thio)amino)-4-methylpentanoic acid dicyclohexylammonium salt; DCHA salt of Nps-Leu; Nps-Leu DCHA
EINECS	Contact for details

Quality Control

Our n-2-Nitrophenylsulfenyl-L-Leucine Dicyclohexylammonium Salt is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, optical rotation, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.