Description

Z-Phe-Pro-Oh is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of phenylalanyl-proline. This compound serves as a crucial building block in peptide synthesis, offering controlled reactivity for the sequential assembly of longer peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biochemical sectors for developing novel therapeutic agents and conducting structure-activity relationship studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, stepwise construction of complex peptides.
• Pharmaceutical Research: Used in the development and screening of peptide-based drug candidates targeting various diseases.
• Biochemical Tool: Employed in enzymatic studies and as a substrate or inhibitor for proteases and other enzymes.
• Custom Peptide Production: Serves as a starting material for contract research organizations (CROs) and CDMOs synthesizing bespoke peptides for clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry, medicinal chemistry, and peptide science.

Basic Information

Product Name	Z-Phe-Pro-Oh
CAS No.	7669-64-9
Molecular Formula	C22H24N2O5
Molecular Weight	396.44 g/mol
Synonyms	N-Carbobenzyloxy-L-phenylalanyl-L-proline; Z-L-Phenylalanyl-L-proline; Z-Phe-Pro; Cbz-Phe-Pro-OH; N-[(Benzyloxy)carbonyl]-L-phenylalanyl-L-proline; N-Cbz-L-Phenylalanyl-L-proline; L-Phenylalanine, N-[(phenylmethoxy)carbonyl]-, (S)-, compel. with L-proline (1:1); Benzyloxycarbonylphenylalanylproline
EINECS	231-637-8

Quality Control

Our Z-Phe-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	-50° to -56° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.