Description

n-Carbobenzoxy-D-Leucine Dicyclohexylammonium Salt is a high-purity, protected amino acid derivative used as a critical chiral building block in organic synthesis. This compound is essential for the controlled synthesis of peptides and peptidomimetics, ensuring the correct stereochemistry is maintained during complex reactions. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-leucine residues with a carbobenzoxy (Cbz) protecting group.
• Biochemical Research: Serves as a standard or reagent in studies involving enzyme substrates, inhibitors, and metabolic pathways.
• Fine Chemical Production: Employed in the custom synthesis of complex organic molecules requiring specific stereochemical configurations.
• Protecting Group Chemistry: Utilized in multi-step synthetic routes where the Cbz group provides orthogonal protection for amino functionalities.

Basic Information

Product Name	n-Carbobenzoxy-D-Leucine Dicyclohexylammonium Salt
CAS No.	7662-58-0
Molecular Formula	C26H42N2O4
Molecular Weight	446.63 g/mol
Synonyms	Z-D-Leucine Dicyclohexylammonium Salt; Cbz-D-Leucine DCHA Salt; D-Leucine, N-[(phenylmethoxy)carbonyl]-, compd. with N-cyclohexylcyclohexanamine (1:1); N-Carbobenzoxy-D-leucine dicyclohexylamine salt; Benzyloxycarbonyl-D-leucine dicyclohexylammonium salt; (R)-2-((Benzyloxycarbonyl)amino)-4-methylpentanoic acid dicyclohexylammonium salt; D-Leucine, N-carboxy-, N-benzyl ester, dicyclohexylammonium salt
EINECS	Contact for details

Quality Control

Our n-Carbobenzoxy-D-Leucine Dicyclohexylammonium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.