Description

Boc-Phe-Gly-Ome CAS NO 7625-57-2 is a protected dipeptide derivative, specifically N-(tert-Butoxycarbonyl)-L-phenylalanylglycine methyl ester, serving as a crucial building block in solid-phase peptide synthesis (SPPS). This compound is valued for its role in constructing complex peptide sequences, where the Boc (tert-butoxycarbonyl) group provides orthogonal protection for the amine functionality. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of therapeutic peptides, biochemical probes, and novel bioactive compounds.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the controlled, sequential assembly of custom peptide chains in both research and process development.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Biochemical Tool Development: Employed to synthesize labeled or modified peptides for use as standards, probes, or substrates in biochemical assays.
• Academic & Institutional Research: A fundamental reagent in university and institutional labs for studying peptide structure, function, and synthesis methodologies.
• Fine Chemical Production: Serves as a starting material or intermediate in the multi-step synthesis of more complex, high-value specialty chemicals.

Basic Information

Product Name	Boc-Phe-Gly-Ome
CAS No.	7625-57-2
Molecular Formula	C₁₇H₂₄N₂O₅
Molecular Weight	336.38 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-phenylalanylglycine methyl ester; Boc-L-phenylalanyl-glycine methyl ester; Boc-Phe-Gly-OMe; Methyl N-[(2S)-2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-1-oxo-3-phenylpropyl]amino]acetate]; (S)-Methyl 2-((2-((tert-butoxycarbonyl)amino)-3-phenylpropanamido)acetate; BOC-PHE-GLY-OME; Boc-Phenylalanine-Glycine-OMe; tert-Butyloxycarbonyl-Phenylalanyl-Glycine Methyl Ester
EINECS	Contact for details

Quality Control

Our Boc-Phe-Gly-Ome is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC for purity and chiral integrity assessment. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-15.0° to -20.0° (c=1 in methanol)
Melting Point	95 - 105 °C
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.