Description

1-Fluoro-1-Deoxy-β-D-Glucose is a fluorinated carbohydrate derivative, specifically a glucose analog where the hydroxyl group at the C-1 position is replaced by fluorine. This structural modification makes it a valuable biochemical tool and a key intermediate in the synthesis of more complex fluorinated sugars and potential pharmaceuticals. It is primarily utilized in research and development within the life sciences and pharmaceutical industries. The compound is of significant interest for studying carbohydrate metabolism and for the development of novel diagnostic agents and therapeutic candidates.

Application

• Biochemical Research: Used as a stable, non-metabolizable analog of glucose to study glucose transport mechanisms and metabolic pathways in cell biology and physiology.
• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of fluorinated nucleosides, glycosidase inhibitors, and other bioactive molecules.
• PET Tracer Development: Acts as a precursor or reference compound in the development of fluorinated radiotracers for Positron Emission Tomography (PET) imaging.
• Glycobiology Studies: Employed to investigate enzyme-substrate interactions, particularly with glycosyltransferases and glycosidases, due to its altered reactivity.
• Chemical Synthesis: Used in organic synthesis to introduce fluorinated sugar moieties into complex natural products or synthetic targets.

Basic Information

Product Name	1-Fluoro-1-Deoxy-β-D-Glucose
CAS No.	7617-95-0
Molecular Formula	C₆H₁₁FO₅
Molecular Weight	182.15 g/mol
Synonyms	1-Deoxy-1-fluoro-β-D-glucopyranose; 1-Fluoro-1-deoxy-β-D-glucopyranose; β-D-Glucopyranose, 1-deoxy-1-fluoro-; 1-FDG (non-radioactive); Fluorodeoxyglucose (non-radioactive); 1-Fluoro-D-glucose; 1-Fluoroglucose; NSC 339756
EINECS	Contact for details

Quality Control

Our 1-Fluoro-1-Deoxy-β-D-Glucose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Our quality systems are designed to support applications requiring high-purity biochemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Optical Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.