Description

(Phenylsulfonyl)Acetonitrile is a versatile organosulfur building block characterized by its reactive nitrile and sulfonyl functional groups. This compound is essential for synthesizing complex heterocyclic structures and fine chemicals, offering a critical pathway for introducing phenylsulfonyl moieties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors.

Application

• Pharmaceutical Intermediate: A key synthon in the preparation of biologically active molecules, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Heterocyclic Chemistry: Serves as a crucial precursor for constructing sulfur and nitrogen-containing heterocycles like thiazoles and pyridines.
• Material Science Research: Employed in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of custom APIs and advanced intermediates.

Basic Information

Product Name	(Phenylsulfonyl)Acetonitrile
CAS No.	7605-28-9
Molecular Formula	C8H7NO2S
Molecular Weight	181.21 g/mol
Synonyms	2-(Phenylsulfonyl)acetonitrile; (Phenylsulfonyl)acetonitrile; Phenylsulfonylacetonitrile; Toluene-α-sulfonylacetonitrile; α-(Phenylsulfonyl)acetonitrile; Benzenesulfonylacetonitrile; (Benzenesulfonyl)acetonitrile; 7605-28-9
EINECS	Contact for details

Quality Control

Our (Phenylsulfonyl)Acetonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.