Description

[(4-tert-Butylphenyl)Thio]Acetonitrile is a specialized organic sulfur compound featuring a tert-butylphenyl group linked to an acetonitrile moiety via a thioether bridge. This unique structure makes it a valuable intermediate and building block in advanced organic synthesis, particularly for the development of pharmaceuticals, agrochemicals, and functional materials. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfur heterocycles or specific aryl-thioether functionalities.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the tert-butylphenyl group confers specific biological activity and stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts due to the electron-donating and steric properties of the tert-butyl group.
• Chemical Research (R&D): A versatile reagent for methodological studies in organic chemistry, including C-S bond formation reactions and cyanoethylation processes.

Basic Information

Product Name	[(4-tert-Butylphenyl)Thio]Acetonitrile
CAS No.	7605-24-5
Molecular Formula	C12H15NS
Molecular Weight	205.32 g/mol
Synonyms	(4-tert-Butylphenylthio)acetonitrile; 2-[(4-tert-Butylphenyl)sulfanyl]acetonitrile; 4-tert-Butylphenyl thiocyanatomethane; p-tert-Butylphenyl thioglycolonitrile; [(p-tert-Butylphenyl)thio]acetonitrile; Acetonitrile, [(4-(1,1-dimethylethyl)phenyl)thio]-; 7605-24-5 (CAS)
EINECS	Contact for details

Quality Control

Our production of [(4-tert-Butylphenyl)Thio]Acetonitrile adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is characterized by modern analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.