Description

Diethyl 2,3-Difluorofumarate is a high-value fluorinated building block and intermediate in organic synthesis. This compound matters for its unique chemical structure, which enables the efficient introduction of fluorine atoms and a reactive fumarate ester moiety into target molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of advanced materials and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, particularly in protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides where fluorine substitution enhances stability and bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and fluorinated materials with unique surface properties.
• Organic Synthesis Reagent: Employed in Diels-Alder reactions, Michael additions, and other cycloaddition chemistry to construct complex, fluorinated heterocycles.
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring new methodologies in fluorination and difunctionalization reactions.

Basic Information

Product Name	Diethyl 2,3-Difluorofumarate
CAS No.	7589-41-5
Molecular Formula	C8H10F2O4
Molecular Weight	208.16 g/mol
Synonyms	2,3-Difluorofumaric Acid Diethyl Ester; Diethyl (E)-2,3-Difluorobut-2-enedioate; (E)-Diethyl 2,3-difluorofumarate; Ethyl 2,3-difluorofumarate; Fumaric acid, 2,3-difluoro-, diethyl ester; Diethyl difluorofumarate
EINECS	Contact for details

Quality Control

Our Diethyl 2,3-Difluorofumarate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container must be kept tightly closed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.