Description

H-Pro-Gly-Gly-Oh CAS NO 7561-25-3 is a high-purity tripeptide derivative consisting of L-proline and two glycine residues. This compound serves as a critical building block and intermediate in advanced peptide synthesis and pharmaceutical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing novel therapeutic peptides, enzyme substrates, or biochemical probes.

Application

• Pharmaceutical Intermediate: A key raw material in the synthesis of longer, more complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard, substrate, or inhibitor in enzymatic studies and proteomics research.
• Peptide Library Construction: Serves as a fundamental building block for combinatorial chemistry and the development of peptide libraries for drug discovery.
• Cosmetic Peptide Synthesis: Employed in the production of specialized peptides for advanced skincare and cosmetic formulations.
• Academic & Industrial R&D: Utilized in universities and corporate labs for investigating peptide structure, function, and metabolism.

Basic Information

Product Name	H-Pro-Gly-Gly-Oh
CAS No.	7561-25-3
Molecular Formula	C9H15N3O4
Molecular Weight	229.23 g/mol
Synonyms	L-Prolylglycylglycine; Pro-Gly-Gly; PGGF; H-Pro-Gly-Gly-OH; Pro-Gly-Gly-OH; L-Pro-Gly-Gly; (S)-1-(2-(2-Aminoacetamido)acetyl)pyrrolidine-2-carboxylic acid; NSC 334855
EINECS	Contact for details

Quality Control

Our H-Pro-Gly-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	-70° to -80° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.