Description

L-Histidine Ethyl Ester is a high-purity derivative of the essential amino acid L-Histidine, widely utilized as a key chiral building block and intermediate in advanced organic synthesis. Its primary commercial value lies in its role in the research and production of complex bioactive molecules, including peptides and pharmaceutical compounds. This product is essential for R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable, high-quality intermediates for their synthesis workflows.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide chemistry.
• Biochemical Research: Serves as a precursor or standard in metabolic studies and enzymatic research.
• Fine Chemical Production: An intermediate for manufacturing specialized chemicals, catalysts, and ligands for asymmetric synthesis.
• Cosmetic & Personal Care Actives: Employed in the development of advanced peptide-based skincare and anti-aging formulations.

Basic Information

Product Name	L-Histidine Ethyl Ester
CAS No.	7555-06-8
Molecular Formula	C8H15N3O2
Molecular Weight	185.22 g/mol
Synonyms	L-Histidine Ethyl Ester Dihydrochloride; Ethyl L-histidinate; H-His-OEt; (2S)-2-Amino-3-(1H-imidazol-5-yl)propanoic acid ethyl ester; Histidine ethyl ester; L-Histidine, ethyl ester; Ethyl (S)-2-amino-3-(1H-imidazol-4-yl)propanoate; L-Histidine Ethyl Ester HCl
EINECS	Contact for details

Quality Control

Our L-Histidine Ethyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting specifications suitable for pharmaceutical research and fine chemical synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.