Description

Ethyl 4-Fluorophenylglycolate is a versatile fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its core value lies in the strategic combination of a reactive glycolate ester moiety and a fluorine-substituted phenyl ring, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, particularly those targeting the central nervous system (CNS) and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Material Research: Serves as a building block for fluorinated mesogens, contributing to improved electro-optical properties in display technologies.
• Advanced Organic Synthesis: Employed in asymmetric synthesis and cross-coupling reactions to introduce chiral α-hydroxy acid derivatives with fluorinated aromatic groups.
• Chemical Research & Development: A valuable reagent for exploring new fluorination methodologies and constructing complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	Ethyl 4-Fluorophenylglycolate
CAS No.	7550-03-0
Molecular Formula	C10H11FO3
Molecular Weight	198.19 g/mol
Synonyms	Ethyl (4-fluorophenyl)(hydroxy)acetate; Ethyl 2-(4-fluorophenyl)-2-hydroxyacetate; 2-Hydroxy-2-(4-fluorophenyl)acetic acid ethyl ester; 4-Fluoromandelic acid ethyl ester; Ethyl α-hydroxy-4-fluorophenylacetate; Glycolic acid, (4-fluorophenyl)-, ethyl ester; Ethyl (4-fluorophenyl)glycolate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Fluorophenylglycolate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet the stringent requirements of fine chemical and pharmaceutical intermediate applications. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.