Description

Boc-L-Asparagine is a high-purity, protected amino acid derivative essential for modern peptide synthesis. Its primary value lies in providing a reactive carboxyl group while protecting the amine functionality with a tert-butoxycarbonyl (Boc) group, which is stable under basic conditions and can be selectively removed under mild acidic conditions. This makes it a critical building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise and efficient solid-phase or solution-phase peptide assembly.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of therapeutic peptides, peptide hormones, and peptidomimetics.
• Biochemical Research: Used in academic and industrial R&D for studying protein structure-function relationships and enzyme mechanisms.
• Combinatorial Chemistry: Serves as a fundamental monomer in the generation of diverse peptide libraries for drug discovery and screening.
• Antibody-Drug Conjugate (ADC) Development: Incorporated into linker-payload constructs for targeted cancer therapies.
• Proteomics & Diagnostics: Employed in the synthesis of labeled peptides used as internal standards in mass spectrometry-based assays.
• Cosmeceutical Peptides: A raw material for synthesizing bioactive peptides used in advanced skincare formulations.

Basic Information

Product Name	Boc-L-Asparagine
CAS No.	7536-55-2
Molecular Formula	C9H16N2O5
Molecular Weight	232.24 g/mol
Synonyms	Nα-(tert-Butoxycarbonyl)-L-asparagine; (S)-2-((tert-Butoxycarbonyl)amino)-3-carbamoylpropanoic acid; Boc-Asn-OH; Boc-L-Asn-OH; N-Boc-L-asparagine; BOC-ASN; Nα-Boc-L-asparagine; N-tert-Butoxycarbonyl-L-asparagine
EINECS	Contact for details

Quality Control

Our Boc-L-Asparagine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and GMP-guided production. We provide comprehensive analytical data, including HPLC purity, chiral purity, and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each batch, detailing compliance with in-house specifications that meet or exceed industry standards for peptide synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Solubility	Clear, colorless solution in DMF or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.