Description

n-[(Benzyloxy)Carbonyl]-L-Alanine 2,4,5-Trichlorophenyl Ester is a protected amino acid derivative widely used as a key building block in peptide synthesis. This compound matters because it offers a reactive ester group for efficient amide bond formation while protecting the L-alanine carboxylic acid moiety, enabling controlled and high-yield coupling reactions. Pharmaceutical researchers and fine chemical manufacturers need it for the development of peptide-based drugs, research peptides, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an activated ester for the controlled incorporation of L-alanine into peptide chains.
• Solution-Phase Peptide Synthesis: Employed in classical peptide coupling strategies for research-scale and small-batch production.
• Pharmaceutical Intermediates: A crucial precursor in the synthesis of complex peptide active pharmaceutical ingredients (APIs).
• Bioconjugation: Used to attach peptide sequences or amino acid motifs to other molecules like proteins, polymers, or surfaces.
• Biochemical Research: Serves as a reagent for studying enzyme mechanisms, protein-protein interactions, and metabolic pathways.
• Production of Custom Peptides: Essential for contract research organizations (CROs) and CDMOs offering bespoke peptide services.

Basic Information

Item	Details
Product Name	n-[(Benzyloxy)Carbonyl]-L-Alanine 2,4,5-Trichlorophenyl Ester
CAS No.	7536-54-1
Molecular Formula	C17H14Cl3NO4
Molecular Weight	402.65 g/mol
Synonyms	Z-L-Ala-OPcp; Z-L-Alanine 2,4,5-Trichlorophenyl Ester; Cbz-L-Alanine 2,4,5-Trichlorophenyl Ester; N-Carbobenzoxy-L-alanine 2,4,5-trichlorophenyl ester; Nα-Cbz-L-alanine 2,4,5-trichlorophenyl ester; (S)-2-(((Benzyloxy)carbonyl)amino)propanoic acid 2,4,5-trichlorophenyl ester; Benzyl N-[(2,4,5-trichlorophenoxy)carbonyl]-L-alaninate
EINECS	Contact for details

Quality Control

Our n-[(Benzyloxy)Carbonyl]-L-Alanine 2,4,5-Trichlorophenyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for peptide synthesis intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.