Description

n-[1,3-Dihydroxy-2-(Hydroxymethyl)Propan-2-Yl]Acetamide is a versatile chemical intermediate characterized by its unique polyol and amide functional groups. This compound is valued for its role as a key building block in the synthesis of more complex molecules, offering reactivity at multiple sites. It is primarily sought after by manufacturers in the pharmaceutical, cosmetic, and specialty chemical industries for applications ranging from drug development to polymer modification.

Application

• Pharmaceutical Synthesis: Serves as a crucial precursor or intermediate in the development of active pharmaceutical ingredients (APIs), particularly for compounds requiring polyhydroxylated or branched structures.
• Cosmetic & Personal Care Ingredients: Used in the formulation of humectants, moisturizers, and skin-conditioning agents due to its hydrophilic and hygroscopic nature.
• Polymer & Resin Modification: Acts as a cross-linking agent or chain extender in the production of specialty polyurethanes, epoxy resins, and other polymers to enhance properties like flexibility or adhesion.
• Bioconjugation & Linker Chemistry: Utilized in biochemical research and diagnostic reagent manufacturing as a spacer or linker molecule for attaching labels, drugs, or probes.
• Chelating Agent Precursor: Its structure makes it a potential starting material for synthesizing ligands used in metal chelation and catalysis.
• Specialty Surfactants: Can be derivatized to produce non-ionic surfactants and emulsifiers for niche industrial and formulation applications.

Basic Information

Product Name	n-[1,3-Dihydroxy-2-(Hydroxymethyl)Propan-2-Yl]Acetamide
CAS No.	7534-51-2
Molecular Formula	C6H13NO4
Molecular Weight	163.17 g/mol
Synonyms	2-Acetamido-2-(hydroxymethyl)-1,3-propanediol; Tris-Acetamide; N-(1,3-Dihydroxy-2-(hydroxymethyl)propan-2-yl)acetamide; 2-Acetamido-2-methylolpropane-1,3-diol; Acetamide, N-[1,3-dihydroxy-2-(hydroxymethyl)-2-propyl]-; Tris base acetamide derivative; THAM-Acetamide
EINECS	231-400-4

Quality Control

Our n-[1,3-Dihydroxy-2-(Hydroxymethyl)Propan-2-Yl]Acetamide is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets precise specifications for identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting these results are available for every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.