Description

Etidronate Disodium CAS NO 7414-83-7 is the disodium salt of etidronic acid, a first-generation bisphosphonate compound. This high-purity active pharmaceutical ingredient (API) is critical for its potent ability to inhibit bone resorption and control mineralization processes. It is an essential raw material for pharmaceutical manufacturers, water treatment formulators, and industrial cleaning solution producers who require a reliable and consistent supply of this specialized chemical.

Application

• Pharmaceutical API: Primary use as the active ingredient in medications for treating Paget's disease of bone, heterotopic ossification, and hypercalcemia of malignancy.
• Oral & Injectable Formulations: Used in the production of both tablet and intravenous (IV) drug formulations requiring precise bone metabolism modulation.
• Industrial Water Treatment: Acts as a highly effective scale and corrosion inhibitor in cooling water systems, boilers, and desalination plants.
• Detergent & Cleaning Agents: Serves as a sequestering agent and builder in industrial and institutional cleaning formulations to control water hardness.
• Personal Care Products: Incorporated into oral care products like toothpaste and mouthwash as an anti-tartar agent.
• Textile & Pulp Processing: Used as a stabilizer and chelating agent in bleaching processes and other chemical treatments.

Basic Information

Product Name	Etidronate Disodium
CAS No.	7414-83-7
Molecular Formula	C2H6Na2O7P2
Molecular Weight	249.99 g/mol
Synonyms	Etidronate Disodium; Disodium Etidronate; (1-Hydroxyethylidene)bisphosphonic Acid Disodium Salt; EHDP Disodium; Etidronic Acid Disodium Salt; Didronel® (Brand Name); HEDP Na2; Disodium (1-Hydroxyethane-1,1-diyl)bis(phosphonate)
EINECS	231-038-9

Quality Control

Our Etidronate Disodium is manufactured under strict quality management systems. We offer material compliant with Pharmaceutical (USP/EP/BP) and high-purity technical grades. Every batch undergoes rigorous analytical testing including assay, impurity profiling, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) is provided with each shipment to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent caking and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	4.0 - 5.5
Water Content (KF)	≤ 12.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C requirements
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.