Description

n-Benzyl-2,2,2-Trifluoro-Acetamide is a specialized trifluoromethylated acetamide derivative, a key building block in advanced organic synthesis. Its value lies in the unique reactivity and stability imparted by the trifluoroacetyl and benzyl groups, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by fine chemical manufacturers producing high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial synthon for the development of new drug candidates, particularly those incorporating fluorinated moieties to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of fluorinated polymers, coatings, or liquid crystals where specific electronic and surface properties are desired.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Detail
Product Name	n-Benzyl-2,2,2-Trifluoro-Acetamide
CAS No.	7387-69-1
Molecular Formula	C9H8F3NO
Molecular Weight	203.16 g/mol
Synonyms	N-Benzyl-2,2,2-trifluoroacetamide; N-(Phenylmethyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(phenylmethyl)acetamide; Benzyltrifluoroacetamide; α,α,α-Trifluoro-N-benzylacetamide; N-Benzyltrifluoroacetamide; BnTFA
EINECS	Contact for details

Quality Control

Our n-Benzyl-2,2,2-Trifluoro-Acetamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.