Description

L-Erythro-Chloramphenicol CAS NO 7384-89-6 is the biologically active stereoisomer of the broad-spectrum antibiotic chloramphenicol. This high-purity compound is critical for research and development in pharmaceutical and life sciences, where precise stereochemistry directly impacts biological activity and efficacy. It is an essential raw material for researchers studying antibiotic mechanisms, resistance, and for the synthesis of advanced pharmaceutical intermediates.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control and assay validation in antibiotic production.
• Biochemical Research: Fundamental tool for studying protein synthesis inhibition, bacterial ribosome function, and mechanisms of antibiotic action.
• Veterinary Medicine Development: Serves as a key intermediate in the formulation of specific veterinary antibiotic treatments.
• Microbiology & Cell Culture: Employed in selective media for cell culture studies and microbiological assays requiring a defined antibiotic agent.
• Organic Synthesis: Acts as a chiral building block or starting material for the synthesis of novel antibiotic analogs and derivatives.

Basic Information

Product Name	L-Erythro-Chloramphenicol
CAS No.	7384-89-6
Molecular Formula	C11H12Cl2N2O5
Molecular Weight	323.13 g/mol
Synonyms	(-)-Chloramphenicol; D-(-)-Threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]acetamide; Chloramphenicol (L-threo isomer); L-Threo-Chloramphenicol; Antibiotic from *Streptomyces venezuelae*; Chloromycetin; Levomycetin; Paraxin
EINECS	230-986-0

Quality Control

Our L-Erythro-Chloramphenicol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, to ensure it meets high-grade specifications suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Erythro isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.