Description

Methyl 2-(Acetylamino)-3-O,4-O,6-o-Trimethyl-2-Deoxy-α-D-Glucopyranoside CAS NO 7380-60-1 is a chemically modified carbohydrate derivative, specifically a protected N-acetylglucosamine analog. This compound is a crucial high-purity building block for advanced organic synthesis and biochemical research. It is primarily utilized by pharmaceutical R&D and specialty chemical manufacturers for developing novel glycoconjugates, glycosidase inhibitors, and complex oligosaccharide mimetics.

Application

• Pharmaceutical Intermediate: Key synthon for the development of glycosidase inhibitors and antiviral/antibacterial agents targeting carbohydrate-processing enzymes.
• Glycobiology Research: Essential building block for the chemical and enzymatic synthesis of complex oligosaccharides and glycoconjugates for structure-activity relationship studies.
• Chemical Biology Probes: Used to create labeled or tagged sugar analogs for studying carbohydrate metabolism and cell-surface interactions.
• Chiral Pool Synthesis: Serves as a valuable chiral starting material for the asymmetric synthesis of natural products and bioactive molecules.
• Standards and Reference Materials: High-purity grade is used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 2-(Acetylamino)-3-O,4-O,6-o-Trimethyl-2-Deoxy-α-D-Glucopyranoside
CAS No.	7380-60-1
Molecular Formula	C₁₂H₂₃NO₆
Molecular Weight	277.31 g/mol
Synonyms	Methyl 2-Acetamido-2-deoxy-3,4,6-tri-O-methyl-α-D-glucopyranoside; Methyl 2-Acetamido-3,4,6-tri-O-methyl-2-deoxy-α-D-glucopyranoside; 2-Acetamido-1,3,4,6-tetra-O-methyl-2-deoxy-α-D-glucopyranose methyl glycoside; 1-O-Methyl-2-acetamido-2-deoxy-3,4,6-tri-O-methyl-α-D-glucopyranoside; N-Acetyl-3,4,6-tri-O-methyl-α-D-glucosamine methyl glycoside; α-Methyl N-acetyl-3,4,6-tri-O-methyl-D-glucosaminide; 7380-60-1; Methyl N-acetyl-3,4,6-tri-O-methyl-α-D-glucosaminide
EINECS	Contact for details

Quality Control

Our Methyl 2-(Acetylamino)-3-O,4-O,6-o-Trimethyl-2-Deoxy-α-D-Glucopyranoside is produced under a strict quality management system. Each batch undergoes rigorous analytical testing including HPLC, NMR, and optical rotation to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with batch-specific data, and can support custom purity requirements for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	+105° to +115° (c=1 in H₂O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.